Daigasso! Band Brothers is a rhythm game series by Nintendo that got it’s start as a Nintendo DS launch title in Japan. While remaining mostly exclusive to Japan, the second game in the series, Daigasso! Band Brothers DX, saw an English release in Europe as Jam with the Band.
The Daigasso! Band Brothers series is unique in that rather than playing to the beat of the music, you are actually playing the individual instruments of a song. All songs in the game let you play any one particular instrument in the song using a variety of control methods depending on the instrument with easier difficulties having simpler controls and the hardest difficulties reach the point of complexity where it basically turns your DS into an actual instrument.
What really makes this series stand out, however, is it’s robust music creation tools. Each new iteration introducing new features and tools for creating music in game which can then be shared with friends or online and be played in game. The latest version on the 3DS even has basic Vocaloid support!